Leukoencephalopathy with cerebral calcifications and cyst: Labrune syndrome.
نویسندگان
چکیده
1 Professor da Faculdade de Medicina da Universidade de Fortaleza, UNIFOR, Fortaleza CE; Médico Neurologista Infantil do Hospital Estadual Albert Sabin, SESA-CE; Médico Colaborador do grupo de neurogenética do Centro de Estudos do Genoma Humano, ICB-USP, São Paulo SP, Brazil; 2 Acadêmico de Medicina da UNIFOR, Fortaleza CE, Brazil; 3 Neurologista do Hospital Geral de FortalezaHGF-SESA-CE, Fortaleza CE, Brazil; 4 Professor Livre-Docente do Departamento de Neurologia da Faculdade de Medicina da Universidade de São Paulo, FMUSP, São Paulo SP, Brazil. Correspondence: André Luiz Santos Pessoa; Rua Monsenhor Bruno 289 / apto. 1.303; 60115-191 Fortaleza CE Brasil; E-mail: [email protected] Conflict of interest: There is no conflict of interest to declare. Received in 23 August 2011; Received in final form 26 October 2011; Accepted 01 November 2011
منابع مشابه
Longitudinal clinical and neuro-radiological findings in a patient with leukoencephalopathy with brain calcifications and cysts (Labrune syndrome)☆
Since she was 4 years old, the patient had exhibited frequent convulsive seizures, and she experienced severe headaches and depression in adulthood. At the age of 37 years, cerebral calcifications were detected, but she exhibited no cognitive or motor problems. She suffered a cerebral haemorrhage at 49 years old and experienced cognitive dysfunction, dysarthria, dysphagia, and left-hemiparesis ...
متن کاملAdult-onset leukoencephalopathy, brain calcifications and cysts: a case report
INTRODUCTION Leukoencephalopathy, brain calcifications and cysts, known as Labrune syndrome, is a rare syndrome. The etiology is unknown; in some cases it is difficult to differentiate from Coats plus syndrome and diagnosed as cerebroretinal microangiopathy with calcifications and cysts. We present the case of a patient with adult leukoencephalopathy, brain calcifications and cysts and discuss ...
متن کاملLate-onset leukoencephalopathy with cerebral calcifications and cysts: case report and review of the literature
BACKGROUND Leukoencephalopathy with calcifications and cysts (LCC or Labrune disease) is a relatively recently defined and exceptionally rare disease in which parenchymal cysts and calcifications within a widespread leukoencephalopathy can cause a broad spectrum of neurological symptoms. The cause of the disease is unknown. Manifestation is usually in childhood or adolescence, while onset in ad...
متن کاملLeukoencephalopathy with calcifications and cysts
RATIONALE Leukoencephalopathy with calcifications and cysts (LCC) is an uncommon entity characterized by edematous leukoencephalopathy, cerebral calcifications, and parenchymal cysts. Due to its rarity, the clinical, radiological, and histopathological features have yet to be well elucidated. PATIENT CONCERNS The first case is a 35-year-old female who was asymptomatic. A giant intracranial cy...
متن کاملTeaching NeuroImages: Adult-onset leukoencephalopathy with intracranial calcifications and cysts (Labrune syndrome).
A 42-year-old woman was admitted for a complex partial seizure. At age 18 years, she had transient diplopia, which was considered a simple strabismus. Current examination revealed a left VI cranial nerve palsy and right arm hyperreflexia. Neuroimaging showed multiple intraparenchymal cystic lesions in white matter (figure), multiple calcifications in basal ganglia, and extensive bilateral leuko...
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 70 3 شماره
صفحات -
تاریخ انتشار 2012